Bernhard Riemann (1826–1866) lived only thirty-nine years and was painfully
shy, yet he reshaped mathematics so thoroughly that a startling number of its landmarks carry
his name. The most down-to-earth is the one that finally said, rigorously, what an integral
is: chop the area under a curve into thin rectangles, add them up, and refine — the
Asked by his teacher
In a single short paper on prime numbers, Riemann made a guess about where a certain function's zeros lie — the Riemann Hypothesis. It controls how the primes are scattered among the integers, and more than 160 years later it is still unproven, carrying a one-million-dollar Millennium Prize for whoever cracks it. Not bad for a sickly, retiring man who died of tuberculosis before forty, leaving behind ideas the rest of us are still chasing.
The full story (with far fewer jokes) is on Wikipedia: Bernhard Riemann — Wikipedia.